Testosterone Attenuates Group 2 Innate Lymphoid Cell-Mediated Airway Inflammation
Volume 21, Issue 9, p2487–2499, 28 November 2017 Jacqueline-Yvonne Cephus, Matthew T. Stier, Hubaida Fuseini, Jeffrey A. Yung, Shinji Toki, Melissa H. Bloodworth, Weisong Zhou, Kasia Goleniewska, and others Highlights The number of ILC2 is increased in women with asthma compared to men with asthma Sex hormones regulate IL-2-dependent ILC2 proliferation and cytokine expression Testosterone […]
Asthma: diagnosis, monitoring and chronic asthma management
NICE guideline [NG80] Published date: November 2017 GuidanceTools and resourcesInformation for the publicEvidenceHistory Overview RecommendationsPutting this guideline into practiceContextRecommendations for research Guidance NICE interactive flowchart – Asthma Quality standard – Asthma This guideline covers diagnosing, monitoring and managing asthma in adults, young people and children. It aims to improve the accuracy of diagnosis, help people to control […]
Endobronchial thermoplasty for asthma
Felix Zamora1, Roy Cho1, Madhuri Rao2, Heidi Gibson3, H. Erhan Dincer1 1Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, 2Division of Foregut and Thoracic Surgery, 3Cardiopulmonary Services, University of Minnesota, Minneapolis, MN, USA . Correspondence to: Felix Zamora, MD. Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, 420 Delaware St. SE, MMC 276, Minneapolis, MN 55455, USA. Email: zamo0038@umn.edu. Abstract: Asthma is […]
Physician perspectives on the burden and management of asthma in six countries: The Global Asthma Physician Survey (GAPS)
BMC Pulmonary Medicine Research article – Open Access – Open Peer Review Kenneth R. Chapman, David Hinds, Peter Piazza,Chantal Raherison,Michael Gibbs,Timm Greulich,Kenneth Gaalswyk,Jiangtao Lin,Mitsuru Adachi and Kourtney J. Davis BMC Pulmonary Medicine – BMC series – open, inclusive and trusted 2017 17:153 https://doi.org/10.1186/s12890-017-0492-5 Open Peer Review reports Abstract Background Despite recognition of asthma as a growing global issue and development of global guidelines, asthma treatment practices vary between countries. Several studies have […]
Detection of pathogens by real-time PCR in adult patients with acute exacerbation of bronchial asthma
Research article – Open Access – Open Peer Review Yutaka Yoshi, Kenichiro Shimizu, Miyuki Morozumi, Naoko Chiba, Kimiko Ubukata, Hironori Uruga, Shigeo Hanada, Hiroshi Wakui, Shunsuke Minagawa, Hiromichi Hara, Takanori Numata, Keisuke Saito, Jun Araya, Katsutoshi Nakayama, Kazuma Kishi and Kazuyoshi Kuwano BMC Pulmonary Medicine BMC series – open, inclusive and trusted 2017 17:150 https://doi.org/10.1186/s12890-017-0494-3 Open Peer Review reports Abstract Background Respiratory tract infection is a major cause of acute exacerbation of bronchial asthma (AEBA). Although recent findings suggest that common bacteria are causally associated with AEBA, […]
Identifying the hidden burden of allergic rhinitis (AR) in community pharmacy: a global phenomenon
Rachel Tan, Biljana Cvetkovski, Vicky Kritikos, David Price, Kwok Yan, Pete Smith and Sinthia Bosnic-Anticevich Asthma Research and Practice 2017 3:8 https://doi.org/10.1186/s40733-017-0036-z Abstract Background Patients with allergic rhinitis often trivialise their condition, self-manage inappropriately, and would benefit from health care intervention. The primary point of health care contact for these self-managing allergic rhinitis patients is the community pharmacy. With the majority of allergic rhinitis […]
Asthma biomarkers in the age of biologics
Allergy, Asthma & Clinical Immunology Harold Kim, Anne K. Ellis, David Fischer, Mary Noseworthy, Ron Olivenstein, Kenneth R. Chapman and Jason Lee Allergy, Asthma & Clinical Immunology 2017, 13:48 | Published on: 17 November 2017 Abstract The heterogeneous nature of asthma has been understood for decades, but the precise categorization of asthma has taken on new clinical importance […]
A joint ERS/ATS policy statement: what constitutes an adverse health effect of air pollution? An analytical framework
European Respiratory Journal 2017 49: 1600419; DOI: 10.1183/13993003.00419-2016 George D. Thurston, Howard Kipen, Isabella Annesi-Maesano, John Balmes, Robert D. Brook, Kevin Cromar, Sara De Matteis, Francesco Forastiere, Bertil Forsberg, Mark W. Frampton, Jonathan Grigg, Dick Heederik, Frank J. Kelly, Nino Kuenzli, Robert Laumbach, Annette Peters, Sanjay T. Rajagopalan, David Rich, Beate Ritz, Jonathan M. Samet, Thomas Sandstrom, Torben Sigsgaard, Jordi Sunyer, Bert Brunekreef Abstract The American Thoracic Society has previously published statements on what constitutes an adverse effect on health of air pollution in 1985 and 2000. We set out to update and broaden these past statements that focused primarily on effects on the respiratory […]
Response to case report: Airway autoimmune responses in severe eosinophilic asthma following low-dose Mepolizumab therapy
Allergy, Asthma & Clinical Immunology 2017, 13:45 | Published on: 3 November 2017 I. J. Pouliquen, P. Howarth, D. Austin, G. Gunn, E. Meyer, R. G. Price and E. Bradford To the Editor, We read with interest the case report and accompanying discussion published by Mukherjee et al. (AACI 2017;13:2) of a 62-year old woman diagnosed with severe […]
Prognostic nomogram for inpatients with asthma exacerbation
BMC Pulmonary Medicine RESEARCH ARTICLE – OPEN ACCESS – OPEN PEER REVIEW Wakae Hasegawa,Yasuhiro Yamauchi Email author,Hideo Yasunaga,Hideyuki Takeshima,Yukiyo Sakamoto,Taisuke Jo,Yusuke Sasabuchi,Hiroki Matsui,Kiyohide Fushimi and Takahide Nagase BMC Pulmonary Medicine BMC series – open, inclusive and trusted 2017 17:108 https://doi.org/10.1186/s12890-017-0450-2 Open Peer Review reports Abstract Background Asthma exacerbation may require a visit to the emergency room as well as hospitalization and can occasionally be fatal. However, there is limited information […]