Author: interasm_wp

InSpire to Promote Lung Assessment in Youth: Evolving the Self-Management Paradigms of Young People With Asthma

Original Paper Pierre Elias1; Nithin O Rajan2, MBA; Kara McArthur3; Clifford C Dacso3,4, MBA, MPH, MD 1Duke University School of Medicine, Durham, NC, United States2BSX Athletics, Houston, TX, United States3The Abramson Center for the Future of Health, Houston, TX, United States4Baylor College of Medicine, Houston, TX, United States Corresponding Author: Kara McArthur The Abramson Center […]

Asthma and respiratory physiology: Putting lung function into perspective

Giuseppe Francesco Sferrazza Papa,Giulia Michela Pellegrino and Riccardo Pellegrino. Article first published online: 24 JUL 2014 DOI: 10.1111/resp.12355 © 2014 Asian Pacific Society of Respirology Abstract Bronchial asthma is a chronic disease characterized by airway hyperresponsiveness, airway inflammation and remodelling. The hypothesis that the illness is inflammatory in nature has recently been challenged by studies showing that airway […]

Long-acting beta-agonists plus inhaled corticosteroids safety: a systematic review and meta-analysis of non-randomized studies

  Research Gimena Hernández, Mónica Avila, Àngels Pont, Olatz Garin, Jordi Alonso, Laurent Laforest,Christopher J Cates and Montserrat Ferrer Author Affiliations Respiratory Research 2014, 15:83  doi:10.1186/1465-9921-15-83 Published: 19 July 2014   Abstract (provisional) Background Although several systematic reviews investigated the safety of long-acting beta-agonists (LABAs) in asthma, they mainly addressed randomized clinical trials while evidence from non-randomized studies has been mostly neglected. We aim to […]

Gene – Gene Interactions Among MCP Genes Polymorphisms in Asthma

Allergy Asthma Immunol Res. 2014 Jul;6(4):333-340. English.Published online 2014 April 07.  http://dx.doi.org/10.4168/aair.2014.6.4.333  Copyright © 2014 The Korean Academy of Asthma, Allergy and Clinical Immunology • The Korean Academy of Pediatric Allergy and Respiratory Disease       June-Hyuk Lee and Choon-Sik Park Respiratory and Allergy Medicine, Interanl Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.  Correspondence to: Choon-Sik Park, […]

Differential serum protein markers and the clinical severity of asthma

  Journal of Asthma and Allergy   Authors: Norbert Meyer,1,2 Sarah Janine Nuss,1 Thomas Rothe,1 Alexander Siebenhüner,1 Cezmi A Akdis,2Günter Menz1 Published Date April 2014 Volume 2014:7 Pages 67 – 75 DOI: http://dx.doi.org/10.2147/JAA.S53920     1Hochgebirgsklinik Davos, Davos-Wolfgang, Switzerland; 2Swiss Institute of Allergy and Asthma Research (SIAF), Davos Platz, Switzerland Background: Asthma is a heterogeneous disease characterized by different clinical phenotypes and the involvement of multiple inflammatory […]

The role of macrolides in asthma: current evidence and future directions

  The Lancet Respiratory Medicine, Early Online Publication, 17 June 2014 doi:10.1016/S2213-2600(14)70107-9 Cite or Link Using DOI This article can be found in the following collections: Infectious Diseases (Anti-infective therapy); Respiratory Medicine (Asthma)   Copyright © 2014 Elsevier Ltd All rights reserved. The role of macrolides in asthma: current evidence and future directions Ernie H C Wong MBBS a b c d, James D Porter MSc a b c, Michael R Edwards PhD a b c, Prof Sebastian L […]

Mechanisms of pathogenesis in allergic asthma: Role of interleukin-23

Yanchun Li and Shucheng Hua   Respirology Volume 19, Issue 5, pages 663–669  Abstract Asthma is a chronic airway inflammatory disease characterized by intense leukocyte and eosinophilic infiltration accompanied by mucus hypersecretion and tissue hyperresponsiveness. Recent evidence suggests that T-helper (Th)2 cells and their cytokine products orchestrate the pathology of asthma. In addition, Th17 cells are implicated in the pathogenesis […]