Human tissue models for a human disease: what are the barriers?
Thorax doi:10.1136/thoraxjnl-2014-206648 Joanna Edwards1, Maria Belvisi2, Sven-Erik Dahlen3, Stephen Holgate4, Anthony Holmes1 +Author Affiliations 1National Centre for the Replacement, Refinement and Reduction of Animals in Research, London, UK2Faculty of Medicine, National Heart & Lung Institute, Imperial College London, London, UK3Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden 4Faculty of Medicine, University of Southampton, Southampton, UK Abstract Asthma represents an area of significant unmet medical […]
Past Presidents
Prof. U. Damas Mora Portugal 1966 – 1969 Prof. Zaida Erycson Finland 1969 – 1972 Prof. Q.Van Ufford Netherlands 1972 – 1975 Prof D. Jonhstone USA 1975 – 1978 Prof. L Jager Deutsch 1978 – 1981 Prof. J. Vialatte France 1981 – 1984 Prof A. Oehling Spain 1985 – 1987 Prof. J. Bellanti USA 1987 […]
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ADAM wearable monitors asthma via app
According to the Centers for Disease Control and Prevention, asthma affects over 25 million adults and children in the US alone, and is responsible for 14.2 million physician visits each year as well as 1.8 million emergency care visits. With that huge – and growing – population of asthma sufferers and the associated costs of treating […]
The minimal clinically important difference of the control of allergic rhinitis and asthma test (CARAT): cross-cultural validation and relation with pollen counts
NPJ PRIMARY CARE RESPIRATORY MEDICINE | ARTICLE OPEN npj Primary Care Respiratory Medicine 25, Article number: 14107 (2015) doi:10.1038/npjpcrm.2014.107 Sander van der Leeuw Thys van der Molen PN Richard Dekhuijzen Joao A Fonseca Frederik A van Gemert Roy Gerth van Wijk Janwillem WH Kocks Helma Oosterom Roland A Riemersma Ioanna G Tsiligianni Letty A de Weger Joanne NG Oude […]
The microbiome in asthma
Yvonne J. Huang, MD Homer A. Boushey, MD R DOI: http://dx.doi.org/10.1016/j.jaci.2014.11.011 Abstract: The application of recently developed sensitive, specific, culture-independent tools for identification of microbes is transforming concepts of microbial ecology, including concepts of the relationships between the vast complex populations of microbes associated with ourselves and with states of health and disease. Although most […]
YKL-40 is correlated with FEV1 and the asthma control test (ACT) in asthmatic patients: influence of treatment
Research article Tianwen Lai, Min Chen, Zaichun Deng, Yingying L¿, Dong Wu, Dongming Li and Bin Wu BMC Pulmonary Medicine 2015, 15:1 doi:10.1186/1471-2466-15-1 Published: 12 January 2015 Abstract (provisional) Background YKL-40 is also called chitinase-3-like-1 (CHI3L1) protein and may be a marker for asthma. The aims of the present study were to investigate whether serum YKL-40 levels are stable or decreased in patients with […]
Sputum eosinophilia is a determinant of FEV1 decline in occupational asthma: results of an observational study
BMJ Open. 2015 Jan 5;5(1):e005748. doi: 10.1136/bmjopen-2014-005748. Talini D1, Novelli F2, Bacci E2, Bartoli M2, Cianchetti S2, Costa F2, Dente FL2, Di Franco A2, Latorre M2, Malagrinò L2, Vagaggini B2, Celi A2, Paggiaro P2. Author information Abstract OBJECTIVE: To evaluate the potential determinants of forced expiratory volume in 1 s (FEV1) decline in workers with occupational asthma (OA) still exposed to the causative agent. We hypothesised that sputum eosinophilia might be […]
Occupational exposures, smoking and airway inflammation in refractory asthma
Research article Jodie L Simpson, Maya Guest, May M Boggess and Peter G Gibson BMC Pulmonary Medicine 2014, 14:207 doi:10.1186/1471-2466-14-207 Published: 19 December 2014 Abstract (provisional) Background The influence of occupation and ex/passive smoking on inflammatory phenotype is not well understood. The aim of this study was to examine the relationship between occupation, past smoking and current passive smoking and airway […]
OBITUARY – CARLOS BAENA-CAGNANI
Carlos Baena Cagnani ci ha lasciato improvvisamente il 31 Dicembre u.s. nei dintorni di Cordoba, Argentina. Ci ha lasciato tutti, nel modo che forse avrebbe desiderato: a cena, circondato dai suoi figli, dai suoi nipoti, dal loro affetto , dalla loro e dalla sua immensa gioia di vivere. Immensa gioia di vivere e di condividere, […]