Eosinophilia in asthma: the easy way is not always the best
Bianca Beghè, Antonio Spanevello, Leonardo M Fabbri DOI: http://dx.doi.org/10.1016/S2213-2600(15)00108-3 According to the latest version of the Global Initiative for Asthma strategy document,1 asthma is a heterogeneous disease with clinical manifestations sustained by different molecular mechanisms; in particular, these manifestations could be (but are not invariably) associated with chronic airway inflammation. Indeed, part of the heterogeneity of […]
Why aren’t we doing better in asthma: time for personalised medicine?
NPJ PRIMARY CARE RESPIRATORY MEDICINE | PERSPECTIVE OPEN npj Primary Care Respiratory Medicine 25, Article number: 15004 (2015) doi:10.1038/npjpcrm.2015.4 Mike Thomas Abstract After decades of improvement, asthma outcomes have stalled. Mortality, hospitalisations, exacerbations and symptom control remain sub-optimal. In controlled trials, most patients gain high levels of control, but in ‘real-life’ routine clinical practice most patients do not. Avoidable factors […]
Bronchial thermoplasty for severe asthma – Nice Guideline
The National Institute for Health and Clinical Excellence (NICE) has issued full guidance to the NHS in England, Wales, Scotland and Northern Ireland on Bronchial thermoplasty for severe asthma. NICE interventional procedure guidance [IPG419] Published date: January 2012 Description Treating severe asthma using radiofrequency (heat) energy. Asthma is a condition that causes the airways to become narrower; the […]
ICS adherence can be improved by integrated asthma care program
Canadian researchers measured asthma control and ICS adherence in 108 asthmatics participating in an integrated asthma care program for a year and 241 asthmatics who had normal care. Participants had uncontrolled or mild-severe asthma at baseline and were recruited by 42 pharmacists. Standardised questionnaires and drug adherence and possession scales were used for assessment. At […]
Asthma Mobile Health Study
Asthma Mobile Health Study With apps powered by Apple’s new ResearchKit, you can easily participate in medical research studies and help contribute to improving health care. Our team at the Icahn School of Medicine at Mount Sinai invites you to join our Asthma Mobile Health study. Asthma Mobile Health Study This app is a […]
Distinct endotypes of steroid-resistant asthma characterized by IL-17Ahigh and IFN-γhigh immunophenotypes: Potential benefits of calcitriol
Emma S. Chambers, PhD∗ Alexandra M. Nanzer, MRCP, Paul E. Pfeffer, MRCP, David F. Richards, MSc, Peter M. Timms, FRCPath, Adrian R. Martineau, PhD, Christopher J. Griffiths, FRCGP, Christopher J. Corrigan, PhD, Catherine M. Hawrylowicz, PhD ∗Dr Chambers is now affiliated with the Division of Infection and Immunity, University College London, London, United Kingdom. Open […]
Interasma Symposia in the Latin American Congress of Allergy, Asthma & Immunology
16/03/2015 – Panamericano Hotel & Convention Center, Buenos Aires, Argentina Tribute tol Prof. Carlos E. Baena-Cagnani, INTERASMA Past President Chairmen: Ignacio Ansotegui, Juan C. Ivancevich 11:15 Introduction: The Global Impact of Asthma G Walter Canonica 11:35 Late Phase Response in Asthma Louis P. Boulet 11:55 Inhalation Challenges in Occupational Asthma Joaquin Sastre […]
Prof. G. Walter Canonica: In memorian: a tribute to Carlos E. Baena-Cagnani in the Latin American Congress SLaai2015
Volatile organic compounds and risk of asthma and allergy: a systematic review
Ulugbek B. Nurmatov, Nara Tagiyeva, Sean Semple, Graham Devereux andAziz Sheikh Abstract Volatile organic compounds (VOCs) are ubiquitous domestic pollutants. Their role in asthma/allergy development and exacerbations is uncertain. This systematic review investigated whether domestic VOC exposure increases the risk of developing and/or exacerbating asthma and allergic disorders. We systematically searched 11 databases and three trial repositories, and […]
Innate immunity is a key factor for the resolution of inflammation in asthma
Eur Respir Rev March 1, 2015vol. 24 no. 135 141-153 Cindy Barnig1 and Bruce D. Levy2 +Author Affiliations 1Dept of Chest Disease, University Hospital of Strasbourg and FMTS (Fédération de Médecine Translationnelle de Strasbourg), Strasbourg, France 2Pulmonary and Critical Care Medicine, Dept of Internal Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA Cindy Barnig, Dept of […]