Bronchial thermoplasty improves asthma regardless of socioeconomic status

Among people with asthma, lower socioeconomic status, education level, and ethnic minority status clearly have undesirable effects on their care and outcomes. Patients with severe disease who attend county (public) hospitals in the United States tend to have less access to resources, which, in addition to environmental and compliance issues, may contribute to poorer disease […]

Bronchial thermoplasty improves asthma regardless of socioeconomic status

Among people with asthma, lower socioeconomic status, education level, and ethnic minority status clearly have undesirable effects on their care and outcomes. Patients with severe disease who attend county (public) hospitals in the United States tend to have less access to resources, which, in addition to environmental and compliance issues, may contribute to poorer disease […]

Patient-physician relationship in the management of asthma: Multicentric approach in Latin America

Just Accepted by Journal of Asthma DOI:10.3109/02770903.2016.1145691 Iván Cherrez Ojeda MD, MScab*, Juan Carlos Calderon MDb, José Mori MDc, Darío Colombaro MDd, Fulvio Braido MDe, Edwin SoriaMDf & Annia Cherrez MDb Abstract Objective: To investigate and compare how Latin American physicians rate themselves on the use of communication strategies in the management of asthma patients, and to explore their personal experience and opinions on asthma treatment. Methods: A cross-sectional survey […]

Development of a nomogram to estimate the Quality of Life (QoL) in asthmatic children by using the Childhood Asthma Control Test (C-ACT)

Accepted Article (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future) Laura Montalbano1,2, Giovanna Cilluffo1,3, Manuel Gentile4,  Giuliana Ferrante5,  Velia Malizia1,  Fabio Cibella1,  Giovanni Viegi1,6, Giovanni Passalacqua7 and Stefania La Grutta1,* Abstract Background: Pediatric Asthma Quality of Life Questionnaire (PAQLQ) provides detailed information on QoL in asthmatic children whereas childhood […]

Long-term efficacy and safety of bronchial thermoplasty in patients with moderate-to-severe persistent asthma: a systemic review and meta-analysis

    Volume 53, Issue 1, 2016 Abstract Objective: To evaluate the long-term efficacy and safety of bronchial thermoplasty (BT) in the treatment of patients with moderate-to-severe persistent asthma. Methods: We therefore performed a systematic literature review of peer-reviewed studies focusing on BT intervention in asthma control published between January 2000 and June 2014. Three randomized controlled […]

Type 2 innate lymphoid cells: at the cross-roads in allergic asthma

Review Article Seminars in Immunopathology pp 1-14 Open Access Leonie van Rijt , Helen von Richthofen, Ronald van Ree Abstract Allergic asthma is a chronic inflammatory disease of the lower airways that affects millions of people worldwide. Allergic asthma is a T helper 2 cell (Th2)-mediated disease, in which Th2 cytokines interleukin (IL)-4, IL-5, and IL-13 are closely associated with the symptoms. IL-4 is […]

Bronchial hyperresponsiveness

Occup Med (Lond) (2016) 66 (2): 95–105 doi:10.1093/occmed/kqv158 J. Borak1,2 and R. Y. Lefkowitz2 Abstract Background Bronchial hyperresponsiveness (BHR) is often regarded as a ‘hallmark’ of asthma and bronchoprovocation testing is frequently performed to support a diagnosis of asthma. However, BHR is also found in a spectrum of other lung diseases and can be provoked by a variety of specific stimuli. Aims To review […]

Long-acting muscarinic antagonists: a potential add-on therapy in the treatment of asthma?

William W. Busse, Ronald Dahl, Christine Jenkins, Alvaro A. Cruz   Abstract Asthma is a chronic inflammatory disorder of the airways that is a major global burden on both individuals and healthcare systems. Despite guideline-directed treatment, a significant proportion of patients with asthma do not achieve control. This review focuses on the potential use of long-acting anticholinergics as bronchodilators in the treatment […]

Treatment of asthma in young children: evidence-based recommendations

    Asthma Research and Practice 2016 2:5 DOI: 10.1186/s40733-016-0020-z   Jose A. Castro-Rodriguez Email author, Adnan Custovic and Francine M. Ducharme Abstract In the present review, we focus on evidence-based data for the use of inhaled corticosteroids (ICS), leukotriene receptor antagonist (LTRA), long-acting beta2-agonits (LABA) and oral corticosteroids (OCS), with a special emphasis on well-performed randomized clinical trials (RCTs) and meta-analyses of such trials for the […]