Bronchial Thermoplasty for Severe Asthma: A Review of the Clinical and Cost-Effectiveness, and Guidelines

  Rapid Response Report: Summary with Critical Appraisal Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2015 Aug 27. Severe asthma is a chronic condition in which patients experience airway inflammation and airway muscle contraction leading to symptoms of breathlessness, wheezing, coughing, and chest tightness. It is one of the most common chronic conditions with an estimated 235 million people affected worldwide, an increasing global […]

Comparison of pulmonary function in patients with COPD, asthma-COPD overlap syndrome, and asthma with airflow limitation

International Journal of Chronic Obstructive Pulmonary Disease » Volume 11 » Issue 1   Yoshiaki Kitaguchi, Masanori Yasuo, Masayuki Hanaoka First Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, JapanBackground: This study was conducted in order to investigate the differences in the respiratory physiology of patients with chronic obstructive pulmonary disease (COPD), asthma-COPD overlap syndrome (ACOS), and asthma […]

Asthma Research and Practice celebrates its first anniversary

As open access journal Asthma Research and Practice celebrates its first anniversary, we are pleased to bring you a selection of recently published articles. We hope you find the articles of interest and invite you to submit your next manuscript to the journal. We also encourage you to read our blog post for World Asthma Day as well as more asthma-related posts. […]

Detailed analysis of sputum and systemic inflammation in asthma phenotypes: are paucigranulocytic asthmatics really non-inflammatory?

RESEARCH ARTICLE – OPEN ACCESS – OPEN PEER REVIEW   Sophie Demarche, Florence Schleich, Monique Henket, Virginie Paulus, Thierry Van Hees and Renaud Louis BMC Pulmonary MedicineBMC series – open, inclusive and trusted 201616:46 DOI: 10.1186/s12890-016-0208-2 Open Peer Review reports Abstract Background The technique of induced sputum has allowed to subdivide asthma patients into inflammatory phenotypes according to their level of granulocyte airway infiltration. There are very few studies […]

LINX®, a novel treatment for patients with refractory asthma complicated by gastroesophageal reflux disease: a case report

Narin Sriratanaviriyakul, Celeste Kivler,, Tamas J. Vidovszky,, Ken Y. Yoneda,, Nicholas J. Kenyon,, Susan Murin and Samuel Louie Journal of Medical Case Reports 201610:124 DOI: 10.1186/s13256-016-0887-6 Open Peer Review reports Abstract Background Gastroesophageal reflux disease is one of the most common comorbidities in patients with asthma. Gastroesophageal reflux disease can be linked to difficult-to-control asthma. Current management includes gastric acid suppression therapy and surgical antireflux procedures. The LINX® procedure is a novel surgical […]

Insights, attitudes, and perceptions about asthma and its treatment: a multinational survey of patients from Europe and Canada

World Allergy Organ J. 2016; 9: 13.   Joaquin Sastre, Leonardo M. Fabbri, David Price, Hans Ulrich Wahn, Jean Bousquet, James E. Fish, Kevin Murphy,and Malcolm R. Sears Abstract Background Asthma surveys completed within the past 10 years in the Americas and the Asia-Pacific region have shown significant underassessment of asthma severity in addition to undertreatment of asthma and have suggested the need […]

Determinants and impact of suboptimal asthma control in Europe: The INTERNATIONAL CROSS-SECTIONAL AND LONGITUDINAL ASSESSMENT ON ASTHMA CONTROL (LIAISON) study

  Respiratory Research 201617:51 DOI: 10.1186/s12931-016-0374-z   Fulvio Braido, Guy Brusselle, Daniele Guastalla, Eleonora Ingrassia, Gabriele Nicolini, David Price, Nicolas Roche, Joan B. Soriano, Heinrich Worth and on behalf of the LIAISON Study Group  Abstract Background According to the Global Initiative of Asthma, the aim of asthma treatment is to gain and maintain control. In the INTERNATIONAL CROSS-SECTIONAL AND LONGITUDINAL ASSESSMENT ON ASTHMA CONTROL (LIAISON) study, we evaluated the level of asthma control and quality of life (QoL), as […]

May 2nd is Now “Bronchial Thermoplasty Awareness Day” in Pennsylvania

 Asthma is a disease that causes the airways of the lungs to swell and narrow, leading to wheeze, shortness of breath, chest tightness, and cough. Asthma is the most common chronic lung disease, affecting up to 10% of adults and 30% of children. Bronchial Thermoplasty (BT) is one of the treatment options for severe asthma – […]

Periostin levels and eosinophilic inflammation in poorly-controlled asthma

RESEARCH ARTICLE – OPEN ACCESS – OPEN PEER REVIEW Jodie L. Simpson Emailauthor, Ian A. Yang, John W. Upham, Paul N. Reynolds, Sandra Hodge, Alan L. James, Christine Jenkins, Matthew J. Peters, Guiquan Jia, Cecile T. J. Holweg and Peter G. Gibson BMC Pulmonary MedicineBMC series – open, inclusive and trusted 2016 16:67 DOI: 10.1186/s12890-016-0230-4 Open Peer Review reports Abstract Background Periostin levels are associated with airway eosinophilia and are suppressed by corticosteroid treatment in asthma. This study sought to determine the relationship between serum and sputum periostin, airway inflammatory phenotype […]