Lung-resident eosinophils represent a distinct regulatory eosinophil subset
J Clin Invest. 2016. doi:10.1172/JCI85664. Claire Mesnil,1,2 Stéfanie Raulier,1 Geneviève Paulissen,1 Xue Xiao,2,3 Mark A. Birrell,4Dimitri Pirottin,1,2 Thibaut Janss,1 Philipp Starkl,5 Eve Ramery,2 Monique Henket,6,7Florence N. Schleich,6,7 Marc Radermecker,8 Kris Thielemans,9 Laurent Gillet,2,3 Marc Thiry,10 Maria G. Belvisi,4 Renaud Louis,6,7 Christophe Desmet,1,2 Thomas Marichal,1,2 and Fabrice Bureau1,2,11 Research Article See the related Commentary A hidden residential cell in the lung. Abstract Increases in eosinophil numbers are associated with infection and allergic diseases, including asthma, […]
Lung-resident eosinophils represent a distinct regulatory eosinophil subset
J Clin Invest. 2016. doi:10.1172/JCI85664. Claire Mesnil,1,2 Stéfanie Raulier,1 Geneviève Paulissen,1 Xue Xiao,2,3 Mark A. Birrell,4Dimitri Pirottin,1,2 Thibaut Janss,1 Philipp Starkl,5 Eve Ramery,2 Monique Henket,6,7Florence N. Schleich,6,7 Marc Radermecker,8 Kris Thielemans,9 Laurent Gillet,2,3 Marc Thiry,10 Maria G. Belvisi,4 Renaud Louis,6,7 Christophe Desmet,1,2 Thomas Marichal,1,2 and Fabrice Bureau1,2,11 Research Article See the related Commentary A hidden residential cell in the lung. Abstract Increases in eosinophil numbers are associated with infection and allergic diseases, including asthma, […]
Factors associated with quality of life in patients with severe asthma: the impact of pharmacotherapy
J Bras Pneumol v.41(6); Nov-Dec 2015 J Bras Pneumol. 2015 Nov-Dec; 41(6): 496–501. doi: 10.1590/S1806-37562015000004545 Daiane Silva Souza, 1 Lúcia de Araújo Costa Beisl Noblat, 2 and Pablo de Moura Santos 1 Author information ► Article notes ► Copyright and License information ► ABSTRACT OBJECTIVE: To identify, characterize, and quantify associations of various factors with quality of life (QoL) in patients with asthma, according to the pharmacotherapy employed. METHODS: This […]
Asthma phenotypes: the intriguing selective intervention with Montelukast
Cottini Marcello and Lombardi Carlo Abstract Asthma is a heterogeneous disease, usually characterized by chronic airway inflammation and a variable course associated with various underlying mechanisms that can differ between individuals. Patients with asthma can therefore exhibit different phenotypes, a term used to define the observable characteristics of an organism resulting from the interaction between […]
The A’s Have It: Developing Apolipoprotein A-I Mimetic Peptides Into a Novel Treatment for Asthma
FREE TO VIEW Xianglan Yao, MD, PhD; Elizabeth M. Gordon, PhD; Amisha V. Barochia, MBBS, MHS; Alan T. Remaley, MD, PhD; Stewart J. Levine, MD Author and Funding Information Chest. 2016;150(2):283-288. doi:10.1016/j.chest.2016.05.035 Abstract Abstract | Insights From Murine Studies Regarding the Role of ApoA-I in Asthma | What Are the Potential Cellular Mechanisms by Which the ApoA-I/ABCA1 Pathway May […]
Long-Term Effects of Bronchial Thermoplasty on Airway Smooth Muscle and Reticular Basement Membrane Thickness in Severe Asthma
khlass Haj Salem, Louis-Philippe Boulet, Sabrina Biardel, Noel Lampron, Simon Martel, Michel Laviolette, and Jamila Chakir, Annals of the American Thoracic Society, Vol. 13, No. 8 (2016), pp. 1426-1428. doi: 10.1513/AnnalsATS.201603-182LE Click to increase image size
Self-perceived Sleep Quality and Quantity in Adults With Asthma: Findings From the CosteAsma Study
Sanz de Burgoa V1, Rejas J2, Ojeda P3 on behalf of the investigators of the Coste Asma study 1Medical Department, Pfizer S.L.U., Alcobendas, Madrid, Spain2Health Economics and Outcomes Research Department, Pfizer S.L.U., Alcobendas, Madrid, Spain3Clínica de Asma y Alergia Dres. Ojeda, Madrid, Spain J Investig Allergol Clin Immunol 2016; Vol 26(4): 256-262doi: 10.18176/jiaci.0044 Abstract Background and […]
Elucidating asthma phenotypes and endotypes: progress towards personalized medicine
May 2016 Volume 116, Issue 5, Pages 394–401 Mauli Desai, MD, John Oppenheimer, MD DOI: http://dx.doi.org/10.1016/j.anai.2015.12.024 Full Text Images References
The World Anti-Doping Code: can you have asthma and still be an elite athlete?
Breathe (Sheff). 2016 Jun; 12(2): 148–158. doi: 10.1183/20734735.004116 Ken Fitch Abstract Key points The World Anti-Doping Code (the Code) does place some restrictions on prescribing inhaled β2-agonists, but these can be overcome without jeopardising the treatment of elite athletes with asthma. While the Code permits the use of inhaled glucocorticoids without restriction, oral and intravenous […]
The efficacy and safety of Reslizumab for inadequately controlled asthma with elevated blood eosinophil counts: a systematic review and meta-analysis
Journal of Asthma: Official Journal of the Association for the Care of Asthma 2016 July 19 Jinfeng Li, Cunzhi Lin, Jianxin Du, Baohong Xiao, Chunhua Du, Jiaxing Sun, Fangfang Wang CONTEXT: Reslizumab is a humanised anti-interleukin 5 monoclonal antibody that disrupts eosinophil maturation and promotes programmed cell death. OBJECTIVE: We carried out a systematic review […]