The epidemiology, healthcare and societal burden and costs of asthma in the UK and its member nations: analyses of standalone and linked national databases
BMC Medicine BMC Medicine 2016 14:113 DOI: 10.1186/s12916-016-0657-8 Mome Mukherjee, Andrew Stoddart, Ramyani P. Gupta, Bright I. Nwaru, Angela Farr, Martin Heaven, Deborah Fitzsimmons, Amrita Bandyopadhyay, Chantelle Aftab, Colin R. Simpson, Ronan A. Lyons, Colin Fischbacher, Christopher Dibben, Michael D. Shields, Ceri J. Phillips, David P. Strachan, Gwyneth A. Davies, Brian McKinstry and Aziz Sheikh Open Peer Review reports Abstract Background There are a lack of reliable data on the epidemiology and associated burden and costs of asthma. We sought to provide the first UK-wide estimates of […]
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Cognitive behavioural therapy (CBT) for adults and adolescents with asthma
Cochrane Database Syst Rev. 2016 Sep 21;9:CD011818. [Epub ahead of print] Kew KM1, Nashed M, Dulay V, Yorke J. Author information 1Population Health Research Institute, St George’s, University of London, Cranmer Terrace, London, UK, SW17 0RE. Abstract BACKGROUND: People with asthma have a higher prevalence of anxiety and depression than the general population. This is associated with […]
Father’s environment before conception and asthma risk in his children
Int. J. Epidemiol. (2016)doi: 10.1093/ije/dyw151 Father’s environment before conception and asthma risk in his children: a multi-generation analysis of the Respiratory Health In Northern Europe study Cecilie Svanes1–3,†, Jennifer Koplin1,4,5,,†, Svein Magne Skulstad3,6,*, Ane Johannessen3,7,Randi Jakobsen Bertelsen2,3, Byndis Benediktsdottir8,9, Lennart Bråbäck10,Anne Elie Carsin11, Shyamali Dharmage3,4, Julia Dratva1,12, Bertil Forsberg10,Thorarinn Gislason8,9, Joachim Heinrich13, Mathias Holm14, Christer Janson15,Deborah Jarvis16, Rain Jögi17,18, Susanne Krauss-Etschmann19, Eva Lindberg15,Ferenc Macsali20, Andrei Malinovschi15, Lars Modig10, Dan Norbäck15, Ernst Omenaas3,7,Eirunn Waatevik Saure3, Torben Sigsgaard21, Trude […]
Advances in Bronchial Thermoplasty
Chest. 2016;150(3):694-704. doi:10.1016/j.chest.2016.03.012 Balaji Laxmanan, MD; Katarine Egressy, MD; Septimiu D. Murgu, MD; Steven R. White, MD; D. Kyle Hogarth, MD, FCCP Author and Funding Information Abstract Abstract | Rationale for Bronchial Thermoplasty | BT: Instruments and Technique | First Randomized Controlled Trials: Asthma Intervention Research and Research in Severe Asthma | The Pivotal and Controversial AIR2 Trial | Long-term Safety and Outcomes | Airway Disease | BT for […]
European Asthma Research and Innovation Partnership
The European Asthma Research and Innovation Partnership (EARIP) aims to reduce asthma deaths in Europe by 25% within ten years and by 50% within 20 years. The partnership, made up of 12 European-based organisations, also aims to halve hospital admission rates, speed up the discovery of new treatments and improve self-management. The EARIP project will […]
Long-Term Effects of Bronchial Thermoplasty on Airway Smooth Muscle and Reticular Basement Membrane Thickness in Severe Asthma
Ikhlass Haj Salem, Louis-Philippe Boulet, Sabrina Biardel, Noel Lampron, Simon Martel, Michel Laviolette, and Jamila Chakir “Long-Term Effects of Bronchial Thermoplasty on Airway Smooth Muscle and Reticular Basement Membrane Thickness in Severe Asthma“, Annals of the American Thoracic Society, Vol. 13, No. 8 (2016), pp. 1426-1428. doi: 10.1513/AnnalsATS.201603-182LE
Enhancing Respiratory Medication Adherence: The Role of Health Care Professionals and Cost-Effectiveness Considerations
September–October, 2016 Volume 4, Issue 5, Pages 835–846 Job F.M. van Boven, Dermot Ryan, MD, Michelle N. Eakin, PhD, Giorgio W. Canonica, MD, Aji Barot, MSc, Juliet M. Foster, PhD on behalf of the Respiratory Effectiveness Group Open Access DOI: http://dx.doi.org/10.1016/j.jaip.2016.03.007 | Article Outline The Role of Primary Health Care Professionals in Optimizing Adherence Structured assessment in consultations […]
What We Mean When We Talk About Adherence in Respiratory Medicine
September–October, 2016 Volume 4, Issue 5, Pages 802–812 Bernard Vrijens, PhD , Alexandra L. Dima, PhD, Eric Van Ganse, MD, PhD, FRCP, Job F.M. van Boven, PharmD, PhD, Michelle N. Eakin, PhD, Juliet M. Foster, PhD, Marijn de Bruin, PhD, Alison Chisholm, MSc, David Price, MD, FRCGP Open Access DOI: http://dx.doi.org/10.1016/j.jaip.2016.05.019 | Article Outline Towards a Common Adherence […]
Association of a PAI-1 Gene Polymorphism and Early Life Infections with Asthma Risk, Exacerbations, and Reduced Lung Function
Abstract Background Plasminogen activator inhibitor-1 (PAI-1) is induced in airways by virus and may mediate asthmatic airway remodeling. We sought to evaluate if genetic variants and early life lower respiratory infections jointly affect asthma risk. Methods We included Latino children, adolescents, and young adults aged 8–21 years (1736 subjects with physician-diagnosed asthma and 1747 healthy controls) […]