Effect of inhaled corticosteroid particle size on asthma efficacy and safety outcomes: a systematic literature review and meta-analysis
RESEARCH ARTICLE OPEN ACCESS BMC Pulmonary Medicine Céline El Baou Email author, Rachael L. Di Santostefano, Rafael Alfonso-Cristancho, Elizabeth A Suarez, David Stempel, Mark L Everard and Neil Barnes BMC Pulmonary MedicineBMC series – open, inclusive and trusted 201717:31 DOI: 10.1186/s12890-016-0348-4 Abstract Background Inhaled corticosteroids (ICS) are the primary treatment for persistent asthma. Currently available ICS have differing particle size due to both formulation and propellant, and it has been […]
Effect of novel inhaler technique reminder labels on the retention of inhaler technique skills in asthma: a single-blind randomized controlled trial
Article | OPEN Iman A. Basheti, Nathir M. Obeidat & Helen K. Reddel npj Primary Care Respiratory Medicine 27, Article number: 9 (2017) doi:10.1038/s41533-017-0011-4 Abstract Inhaler technique can be corrected with training, but skills drop off quickly without repeated training. The aim of our study was to explore the effect of novel inhaler technique labels on the retention of correct inhaler […]
Airway and Serum Biochemical Correlates of Refractory Neutrophilic Asthma
Article in Press Rafeul Alam, MD, PhD, James Good, MD, Donald Rollins, MD, Mukesh Verma, PhD, HongWei Chu, MD, Tuyet-Hang Pham, MT, Richard J. Martin, MD DOI: http://dx.doi.org/10.1016/j.jaci.2016.12.963 Abstract Background Despite the progress in diagnosis and management of asthma, many patients have poorly controlled or refractory asthma. The mechanism of this refractory asthma is not well […]
Association of stem cell factor gene expression with severity and atopic state in patients with bronchial asthma
Respiratory Research RESEARCH – OPEN ACCESS Safaa I. Tayel, Sally M. El-Hefnway, Eman M. Abd El Gayed and Gehan A. Abdelaal Respiratory Research 201718:21 DOI: 10.1186/s12931-017-0504-2 Abstract Background Bronchial asthma is a chronic inflammatory and remodeling disorder of the airways, in which many cells, cellular elements, and cytokines play important roles. Stem cell factor (SCF) may contribute to the inflammatory changes occurring in asthma. We aimed […]
Gender-specific determinants of asthma among U.S. adults
Asthma Research and Practice RESEARCH – OPEN ACCESS Rebecca Greenblatt†, Omar Mansour†, Edward Zhao, Michelle Ross and Blanca E Himes Email author Asthma Research and Practice 2017 3:2 Abstract Background Asthma, a chronic respiratory disease affecting over 18.7 million American adults, has marked disparities by gender, race/ethnicity and socioeconomic status. Our goal was to identify gender-specific demographic and socioeconomic determinants of […]
Asthma costs and social impact
Asthma Research and Practice REVIEW – OPEN ACCESS Carlos Nunes, Ana Margarida Pereira and Mário Morais-Almeida Asthma Research and Practice 2017 3:1 DOI: 10.1186/s40733-016-0029-3 Abstract In recent decades, both asthma prevalence and incidence have been increasing worldwide, not only due to the genetic background, but mainly because of the effect of a wide number of environmental and lifestyle risk factors. In many […]
Respiratory effect of beta-blockers in people with asthma and cardiovascular disease: population-based nested case control study
BMC Medicine Daniel R. Morales, Brian J. Lipworth, Peter T. Donnan, Cathy Jackson and Bruce Guthrie BMC Medicine 2017 15:18 DOI: 10.1186/s12916-017-0781-0 Abstract Background Cardiovascular disease (CVD) is a common comorbidity in people with asthma. However, safety concerns have caused heterogeneity in clinical guideline recommendations over the use of cardioselective beta-blockers in people with asthma and CVD, partly […]
Respiratory effect of beta-blockers in people with asthma and cardiovascular disease: population-based nested case control study
BMC Medicine Daniel R. Morales, Brian J. Lipworth, Peter T. Donnan, Cathy Jackson and Bruce Guthrie BMC Medicine 2017 15:18 DOI: 10.1186/s12916-017-0781-0 Abstract Background Cardiovascular disease (CVD) is a common comorbidity in people with asthma. However, safety concerns have caused heterogeneity in clinical guideline recommendations over the use of cardioselective beta-blockers in people with asthma and CVD, partly […]
What patients really think about asthma guidelines: barriers to guideline implementation from the patients’ perspective
BMC Pulmonary Medicine H. Lingner, B. Burger, P. Kardos, C. P. Criée, H. Worth and E. Hummers-Pradier BMC Pulmonary Medicine BMC series – open, inclusive and trusted 201717:13 DOI: 10.1186/s12890-016-0346-6 Abstract Background Treatment of asthma does not always comply with asthma guidelines (AG). This may be rooted in direct or indirect resistance on the doctors’ […]
Subtypes of asthma based on asthma control and severity: a latent class analysis
Respiratory Research 2017 Jan 23;18(1):24. doi: 10.1186/s12931-017-0508-y. Mäkikyrö EM, Jaakkola MS, Jaakkola JJ Abstract BACKGROUND: Asthma subtyping is a complex new field of study. Usually both etiological and outcome factors of asthma have been used simultaneously for subtyping thus making the interpretation of the results difficult. Identification of subtypes of asthma based on questionnaire data only will be […]