Utility of serum eosinophil-derived neurotoxin (EDN) measurement by ELISA in young children with asthma
January 2017Volume 66, Issue 1, Pages 70–74 Chang-Keun Kim, Zak Callaway, Jin-Sung Park, Eunmi Kwon Open Access DOI: http://dx.doi.org/10.1016/j.alit.2016.05.008 | Open access funded by Japanese Society of Allergology Article Outline Introduction Methods Development of EDN antibody Sandwich ELISA Subjects Specimen collection and measurements Blood specimen collection Serum specimen collection Serum EDN measurement Statistical analysis Results Subject […]
A comparison of seasonal trends in asthma exacerbations among children from geographic regions with different climates
Allergy and Asthma Proceedings Allergy Asthma Proc. 2016 Nov-Dec; 37(6): 475–481. doi: 10.2500/aap.2016.37.3994 PMCID: PMC5080535 Julia A. Wisniewski, M.D.,1 Anne P. McLaughlin, M.D.,1 Philip J. Stenger, M.S.,2 James Patrie, M.S.,3 Mark A. Brown, M.D.,4 Jane M. El-Dahr, M.D.,5 Thomas A.E. Platts-Mills, M.D., Ph.D.,1 Nora J. Byrd, M.S.H.A., M.B.A.,6 and Peter W. Heymann, M.D.1 Abstract Background: The fall peak in childhood asthma exacerbations is thought to be […]
Asthma: epidemiology of disease control in Latin America – short review
Asthma Research and Practice REVIEW – OPEN ACCESS Dirceu Solé, Carolina Sanchez Aranda and Gustavo Falbo Wandalsen Asthma Research and Practice 2017 3:4 DOI: 10.1186/s40733-017-0032-3 Abstract Asthma is reported as one of the most common chronic diseases in childhood, impairing the quality of life of patients and their families and incurring high costs to the healthcare system and society. Despite the development of new […]
Interventions to improve adherence to inhaled steroids for asthma
Issue 4. Art. No.: CD012226. DOI: 10.1002/14651858.CD012226.pub2. Normansell R, Kew KM, Stovold E. NewReviewIntervention Abstract Background Despite its proven efficacy in improving symptoms and reducing exacerbations, many patients with asthma are not fully adherent to their steroid inhaler. Suboptimal adherence leads to poorer clinical outcomes and increased health service utilisation, and has been identified as a contributing factor […]
Lung sound analysis helps localize airway inflammation in patients with bronchial asthma
Journal of Asthma and Allergy » Volume 2017:10 Pages 99—108 ORIGINAL RESEARCH Terufumi Shimoda,1 Yasushi Obase,2 Yukio Nagasaka,3 Hiroshi Nakano,1 Akiko Ishimatsu,1 Reiko Kishikawa,1 Tomoaki Iwanaga11Clinical Research Center, Fukuoka National Hospital, Fukuoka, 2Second Department of Internal Medicine, School of Medicine, Nagasaki University, Nagasaki, 3Kyoto Respiratory Center, Otowa Hospital, Kyoto, Japan Purpose: Airway inflammation can be detected by lung sound analysis (LSA) at a single point in […]
The US Food and Drug Administration’s drug safety recommendations and long-acting beta2-agonist dispensing pattern changes in adult asthma patients: 2003–2012
J Asthma Allergy. 2017; 10: 67–74. Published online 2017 Mar 16. doi: 10.2147/JAA.S124395 PMCID: PMC5360406 Esther H Zhou,1 Sally Seymour,2 Margie R Goulding,1 Elizabeth M Kang,1 Jacqueline M Major,1 and Solomon Iyasu1 Author information ► Copyright and License information ► Abstract Background Emerging safety issues associated with long-acting beta2-agonist (LABA) have led to multiple regulatory activities by the US Food and Drug Administration (FDA) since 2003, […]
Effectiveness and success factors of educational inhaler technique interventions in asthma & COPD patients: a systematic review
Review Article | OPEN Sven L. Klijn, Mickaël Hiligsmann, Silvia M. A. A. Evers, Miguel Román-Rodríguez, Thys van der Molen & Job F. M. van Boven npj Primary Care Respiratory Medicine 27, Article number: 24 (2017) doi:10.1038/s41533-017-0022-1 Abstract With the current wealth of new inhalers available and insurance policy driven inhaler switching, the need for insights […]
Asthma in the elderly: a double-blind, placebo-controlled study of the effect of montelukast
Asthma Research and Practice SHORT REPORT – OPEN ACCESS Michele Columbo Asthma Research and Practice 3:3, 2017 DOI: 10.1186/s40733-017-0031-4 Published: 17 April 2017 Abstract Background Little is known about asthma in the elderly as most studies of this condition have not included this patient group. It is unclear whether leukotriene antagonists benefit older asthmatics. We studied the effect of adding […]
Reported Exercise-Related Respiratory Symptoms and Exercise-Induced Bronchoconstriction in Asthmatic Children
J Clin Med Res v.9(5); 2017 May J Clin Med Res. 2017 May; 9(5): 410–415. Published online 2017 Apr 1. doi: 10.14740/jocmr2935w PMCID: PMC5380174 Demet Inci, Refoel Guggenheim, Derya Ufuk Altintas, Johannes H. Wildhaber and Alexander Moeller Author information ► Article notes ► Copyright and License information ► Abstract Background Unlimited physical activity is one of the key issues of asthma control and management. We investigated how reliable […]
Asthma Control and Sputum Eosinophils: A Longitudinal Study in Daily Practice
Articles in Press Sophie F. Demarche, Florence N. Schleich, MD, PhD, Virginie A. Paulus, MLT, Monique A. Henket, MLT, Thierry J. Van Hees, MPharm, PhD, Renaud E. Louis, MD, PhD Abstract Background Longitudinal trials have suggested that asthma control may be influenced by fluctuations in eosinophilic inflammation. This association has however never been confirmed in […]