Anti-Interleukin 5 (IL-5) and IL-5Ra Biological Drugs: Efficacy, Safety, and Future Perspectives in Severe Eosinophilic Asthma

REVIEW ARTICLE Front. Med., 31 August 2017 | https://doi.org/10.3389/fmed.2017.00135 Diego Bagnasco1, Matteo Ferrando1, Gilda Varricchi2, Francesca Puggioni3, Giovanni Passalacqua1 and Giorgio Walter Canonica1,3* 1Allergy and Respiratory Diseases, DIMI Department of Internal Medicine, University of Genoa, IRCCS AOU San Martino-IST, Genoa, Italy2Department of Translational Medical Sciences, Division of Clinical Immunology and Allergy, University of Naples Federico II, Naples, Italy3Department of Internal Medicine, Respiratory […]

The Unresolved Role of Interferon-λ in Asthma Bronchiale

Frontiers in Immunology  vol. 8, p. 989, 2017 Nina Sopel, Andreas Pflaum†, Julia Kölle† and Susetta Finotto* Department of Molecular Pneumology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsklinikum Erlangen, Erlangen, Germany Asthma bronchiale is a disease of the airways with increasing incidence, that often begins during infancy. So far, therapeutic options are mainly symptomatic and thus there is an increasing need for better treatment […]

Asthma Research and Practice

Aims and scope Asthma Research and Practice is the official publication of Interasma and publishes cutting edge basic, clinical and translational research in addition to hot topic reviews and debate articles relevant to asthma and related disorders (such as rhinitis, COPD overlapping syndrome, sinusitis). The journal has a specialized section which focusses on pediatric asthma research. Asthma […]

Asthma management among allergists in Italy: results from a survey

Asthma management among allergists in Italy: results from a survey Juan Carlos Ivancevich Saturday, 26 August 2017 21:54 Clinical and Molecular Allergy RESEARCH – OPEN ACCESS Clinical and Molecular Allergy 2017 15:11 https://doi.org/10.1186/s12948-017-0067-2 M. S. Magnoni, M. Caminati, G. W. Canonica, F. Arpinelli, A. Rizzi and G. Senna Abstract Background In Europe more than 50% of asthmatic […]

Ambient ozone and asthma hospital admissions in Texas: a time-series analysis

Ambient ozone and asthma hospital admissions in Texas: a time-series analysis Asthma Research and Practice RESEARCH – OPEN ACCESS   Julie E. Goodman, Ke Zu, Christine T. Loftus, Ge Tao, Xiaobin Liu and Sabine Lange Asthma Research and Practice 20173:6 – https://doi.org/10.1186/s40733-017-0034-1 Abstract Background Many studies have evaluated associations between asthma emergency department (ED) visits, hospital admissions (HAs), and ambient ozone (O3) across the US, but not in […]

Asthma management among allergists in Italy: results from a survey

Clinical and Molecular Allergy RESEARCH – OPEN ACCESS Clinical and Molecular Allergy 2017 15:11 https://doi.org/10.1186/s12948-017-0067-2 M. S. Magnoni, M. Caminati, G. W. Canonica, F. Arpinelli, A. Rizzi and G. Senna Abstract Background In Europe more than 50% of asthmatic treated patients have not well-controlled asthma. Asthma affects about 2.5 million of patients in Italy. Aims and objectives […]

Emerging understanding of the mechanism of action of Bronchial Thermoplasty in asthma

 Available online 27 July 201 In Press, Corrected Proof   Associate editor: J. Burgess J.N.S.d’Hooghea. N.H.T.ten Hackenb. E.J.M.Weersinka. P.J.Sterka. J.T.Annemaa. P.I.Bontaa.    https://doi.org/10.1016/j.pharmthera.2017.07.015Get rights and content Abstract Bronchial Thermoplasty (BT) is an endoscopic treatment for moderate-to-severe asthma patients who are uncontrolled despite optimal medical therapy. Effectiveness of BT has been demonstrated in several randomized clinical trials. […]

Prognostic nomogram for inpatients with asthma exacerbation

BMC Pulmonary Medicine RESEARCH ARTICLE – OPEN ACCESS – OPEN PEER REVIEW Wakae Hasegawa, Yasuhiro Yamauchi, Hideo Yasunaga, Hideyuki Takeshima, Yukiyo Sakamoto, Taisuke Jo, Yusuke Sasabuchi, Hiroki Matsui, Kiyohide Fushimi and Takahide Nagase BMC Pulmonary Medicine BMC series – open, inclusive and trusted 2017 17:108 https://doi.org/10.1186/s12890-017-0450-2 Abstract Background Asthma exacerbation may require a visit to the emergency room […]

Bronchial thermoplasty: implementing best practice in the era of cost containment

Journal of Asthma and Allergy » Volume 2017:10 Pages 225—230 Laren D Tan,1 Nicholas Kenyon,2 Ken Y Yoneda,2 Samuel Louie2 1Division of Pulmonary, Critical Care, Hyperbaric and Sleep Medicine, Department of Internal Medicine, School of Medicine, Loma Linda University, Loma Linda, CA, USA; 2Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, School of Medicine, University of California, Davis, […]

Bronchial thermoplasty induces immunomodulation with a significant increase in pulmonary CD4+25+ regulatory T cells

Mateja Marc Malovrh, PhD, MD, Mateja Marc Malovrh, Aleš Rozman, PhD, MD, Sabina Škrgat, PhD, MD, Mira Šilar, BSc, Julij Šelb, PhD, MD, Matjaž Fležar, PhD, MD, Peter Korošec, PhD   DOI: http://dx.doi.org/10.1016/j.anai.2017.06.019   Abstract Bronchial thermoplasty (BT) is a method of treating airways and randomized prospective trials have shown positive clinical effects of BT in […]