Bronchial thermoplasty: When is it needed to treat asthma | Prof. Thomas B Casale

Asthma with bronchial hypersecretion: expression of mucins and toll-like receptors in sputum and blood
ORIGINAL RESEARCH Authors Crespo-Lessmann A, Mateus E, Torrejón M, Belda A, Giner J, Vidal S, Sibila O, Plaza V Published 12 October 2017 Volume 2017:10 Pages 269—276 DOI https://doi.org/10.2147/JAA.S142200 Astrid Crespo-Lessmann,1 Eder Mateus,1,2Montserrat Torrejón,1 Alicia Belda,1 Jordi Giner,1Silvia Vidal,2 Oriol Sibila,1 Vicente Plaza,1 1Service of Pneumology, Hospital de la Santa Ceu i Sant Pau, Institute of Sant Pau Biomedical Research (IBB Sant Pau), Universitat Autònoma […]
Chronic obstructive pulmonary disease, bronchial asthma and allergic rhinitis in the adult population within the commonwealth of independent states: rationale and design of the CORE study
BMC Pulmonary Medicine BMC series – open, inclusive and trusted 17:131, 2017 https://doi.org/10.1186/s12890-017-0471-x Open Peer Review reports Yuriy Feshchenko, Liudmila Iashyna, Damilya Nugmanova, Olga Gyrina, Marina Polyanskaya, Alexander Markov, Maryna Moibenko, Janina MakarovaEmail author, Luqman Tariq, Marcelo Horacio S. Pereira, Elcan Mammadbayov, Irada Akhundova and Averyan Vasylyev Abstract Background Main treatable Chronic Respiratory Diseases (CRDs) like Chronic […]
Non adherence to inhalational medications and associated factors among patients with asthma in a referral hospital in Ethiopia, using validated tool TAI
Asthma Research and Practice 2017 3:7 https://doi.org/10.1186/s40733-017-0035-0 Asnakew Achaw Ayeler and Henok Getachew Tegegn Abstract Background Asthma is a chronic inflammatory condition of the airways that affects roughly 358 million people globally. It is a serious global health problem with an increasing prevalence worldwide. Most people affected are in low- and middle-income countries including Ethiopia. The association between non -adherence and […]
Response to omalizumab using patient enrichment criteria from trials of novel biologics in asthma
Browse Early View Articles Online Version of Record published before inclusion in an issue T. B. Casale, B. E. Chipps, K. Rosén, B. Trzaskoma, T. Haselkorn, T. A. Omachi, S. Greenberg, N. A. Hanania Abstract Background Recent efficacy studies of asthma biologics have included highly enriched patient populations. Using a similar approach, we examined factors that […]
Risks associated with managing asthma without a preventer: urgent healthcare, poor asthma control and over-the-counter reliever use in a cross-sectional population survey
BMJ Open Respiratory medicine-Research BMJ Open 2017;7:e016688. doi:10.1136/bmjopen-2017-016688 Helen K Reddel1, ,Rosario D Ampon1, ,Susan M Sawyer2,3,4, ,Matthew J Peters5 Abstract Objectives Overuse of asthma relievers, particularly without anti-inflammatory preventers, increases asthma risks. This study aimed to identify how many reliever-only users have urgent healthcare, explore their attitudes and beliefs about asthma and its treatment, and investigate whether […]
Health Effects of Air Pollution: A Historical Review and Present Status
Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene) Vol. 72 (2017) No. 3 p. 159-165 http://doi.org/10.1265/jjh.72.159 Masayuki SHIMA1) 1) Department of Public Health, Hyogo College of Medicine Abstract During the 1960s, the concentrations of air pollutants, particularly that of sulfur dioxide (SO2), were extremely high in many industrial cities in Japan, and the prevalence of bronchial asthma and chronic […]
Adverse drug reactions of montelukast in children and adults
Open AccessCreative Commons Pharma Res Per, 5(5), 2017, e00341 Meindina G. Haarman, Florence van Hunsel, Tjalling W. de Vries Abstract Montelukast, a selective leukotriene receptor antagonist, is recommended in guidelines for the treatment of asthma in both children and adults. However, its effectiveness is debated, and recent studies have reported several adverse events such as […]
Raw Cow’s Milk Prevents the Development of Airway Inflammation in a Murine House Dust Mite-Induced Asthma Model
Front Immunol. 2017; 8: 1045. doi: 10.3389/fimmu.2017.01045 PMCID: PMC5581320 Suzanne Abbring,1,† Kim A. T. Verheijden,1,† Mara A. P. Diks,1 Athea Leusink-Muis,1 Gert Hols,2 Ton Baars,3 Johan Garssen,1,2 and Betty C. A. M. van Esch1,2,* Author information ► Article notes ► Copyright and License information ► Abstract Epidemiological studies show an inverse relation between raw cow’s milk consumption and the development of asthma. This protective effect seems to be abolished […]
Long-term outcomes of bronchial thermoplasty in subjects with severe asthma: a comparison of 3-year follow-up results from two prospective multicentre studies
Geoffrey Chupp, Michel Laviolette, Lauren Cohn, Charlene McEvoy, Sandeep Bansal, Adrian Shifren, Sumita Khatri, G. Mark Grubb, Edmund McMullen, Racho Strauven, Joel N. Kline European Respiratory Journal 2017 50: 1700017; DOI: 10.1183/13993003.00017-2017 Abstract Bronchial thermoplasty is an endoscopic therapy for severe asthma. The previously reported, randomised sham-controlled AIR2 (Asthma Intervention Research 2) trial showed a significant reduction in severe asthma exacerbations, emergency department visits and hospitalisations after bronchial thermoplasty. More “real-world” clinical outcome data is needed. This article compares outcomes […]