Peripheral blood eosinophilia in adult asthmatic patients and its association with the severity of asthma
Yenealem Solomon, Birhanemaskal Malkamu, Ayenew Berhan, Tahir Eyayu, Andargachew Almaw, Biruk Legese & Berhanu Woldu BMC Pulmonary Medicine volume 23, Article number: 96 (2023) Abstract Background Asthma is a diverse disease with various etiologic bases. Severe asthma can be associated with increased mortality, hospitalization, and decreased quality of life for asthma patients. High blood eosinophil counts were associated with severe asthma, but recent studies have failed […]
New for Journal of Asthma online
Case Report Outcomes of Children with Life-Threatening Status Asthmaticus Requiring Isoflurane Therapy and Extracorporeal Life SupportSneha Kolli MD, Cydney Opolka BS, Adrianna Westbrook MPH, Scott Gillespie MS, MSPH, Carrie Mason RT, Brittany Truitt MD, Pradip Kamat MD, MBA, Anne Fitzpatrick PhD & Jocelyn R. Grunwell MD, PhDPages: 1-15 | DOI: 10.1080/02770903.2023.2191715This is the author accepted […]
Immunoregulation of asthma by type2 cytokine therapies – treatments for all ages?
Saglani S, Yates L, Lloyd CM. Eur J Immunol. 2023 Mar 17:e2249919. doi: 10.1002/eji.202249919. Free Access Abstract Asthma is classically considered to be a disease of type 2 immune dysfunction, since many patients exhibit the consequences of excess secretion of cytokines such as IL-4, IL-5 and IL-13 concomitant with inflammation typified by eosinophils. Mouse and […]
Dietary patterns, lung function and asthma in childhood: a longitudinal study
Research – Open Access Mohammad Talaei, Pauline M. Emmett, Raquel Granell, Hossein Tabatabaeian, Kate Northstone, Anna Bergström & Seif O. Shaheen Respiratory Research volume 24, Article number: 82 (2023) Abstract Background Longitudinal epidemiological data are scarce examining the relationship between dietary patterns and respiratory outcomes in childhood. We investigated whether three distinct dietary patterns in mid-childhood were associated with lung function and incident asthma in adolescence. Methods […]
New for Journal of Asthma online now:
Article Commentary Redefining biomarkers in pediatric asthma: A commentaryRussell J. Hopp D.O. FAAP, FAAAAI, Professor of Pediatrics, Mark C. Wilson M.D., FAAP, FCCP, Associate Professor of Pediatrics, Emeritus & M. Asghar Pasha M.D. FAAAAI, Professor of Medicine and PediatricsPages: 1-12 | DOI: 10.1080/02770903.2023.2189947This is the author accepted version which has not been proofed or edited […]
Redefining the role of bronchoscopy in the work-up of severe uncontrolled asthma in the era of biologics: a prospective study
ABSTRACT Background Severe uncontrolled asthma (SUA) is frequently treated with biologic therapy if a T2 phenotype is found. Bronchoscopy is not routinely recommended in these patients unless a specific indication to rule out comorbidities is present. Research question Is routine bronchoscopy safe and useful in phenotyping and endotyping SUA patients prior to the indication of […]
Dysfunctional Breathing in Asthma Is Most Frequent in Adolescent Girls
Ron Goldberg Children and adolescents with asthma, particularly adolescent girls with asthma, frequently have comorbid dysfunctional breathing (DB), which is correlated with poorer asthma control and higher use of beta2 agonists (β2), according to survey findings published in Pediatric Allergy and Immunology. Investigators sought to estimate DB prevalence in children and adolescents with asthma and to […]
Asthma Exacerbations in Severe Asthma: Why Systemic Corticosteroids May not Always Be the Best Treatment Option
P. Jane McDowell PhD MBBS, J. Busby PHD & Liam G. Heaney MD Abstract Purpose Advances in the management of severe, eosinophilic asthma have improved, but asthma exacerbations continue to occur. This review aims to look at the evidence we have about why exacerbations may occur; their phenotype and why oral corticosteroids may not always be the best […]
Journal of Asthma, Volume 60, Issue 3, March 2023 is now available online
This new issue contains the following articles: Reviews Factors associated with future hospitalization among children with asthma: a systematic reviewSimran Aggarwal MD Candidate, Tanita Cepalo BSc, Sana Gill MD, Madhura Thipse MD, Kerry-Lee Clifton MD Candidate, Andrea Higginson RN, MScN, CAE, James Vu MD, Vid Bijelić MSc, Nick Barrowman PhD, Sandra Giangioppo MD & Dhenuka […]
New for Journal of Asthma online now on Taylor & Francis Online:
Research Article Vitamin D supplementation for children with mild to moderate asthma: an economic evaluationJefferson Antonio Buendía MD, PhD, Diana Guerrero Patiño RN, MSc & Erika Fernanda Lindarte MScPages: 1-9 | DOI: 10.1080/02770903.2023.2178007 Dupilumab long-term efficacy in patients with non–OCS–dependent asthma with and without evidence of allergic asthmaLawrence D. Sher MD, Jonathan Corren MD, Ian […]