New for Journal of Asthma online now:
Case Report Omalizumab rescue therapy in refractory status asthmaticusSanjana Chetana Shanmukhappa, Arun Kumar, Akash Dey, Janani J.V.S, Srivatsa Lokeshwaran, Sunil Kumar K, Prakash Doraiswamy, Shashank M R & Lakshmi GayathriPages: 1-9 | DOI: 10.1080/02770903.2023.2233606This is the author accepted version which has not been proofed or edited Another case of preventable death from AsthmaCinthia Vila Nova […]
Clinic versus home spirometry for monitoring lung function in patients with asthma
Oppenheimer J, Hanania NA, Chaudhuri R et al. Chest. 2023 Jun 27:S0012-3692(23)00935-2. doi: 10.1016/j.chest.2023.06.029. Epub ahead of print. Abstract Background Studies examining agreement between home and clinic spirometry in patients with asthma are limited, with conflicting results. Understanding the strengths and limitations of telehealth and home spirometry is particularly important considering the SARS-CoV-2 pandemic. Research […]
DISPOSITION OF WORK-RELATED ASTHMA IN A SPANISH ASTHMA COHORT: COMPARISON OF ASTHMA SEVERITY BETWEEN EMPLOYED AND RETIRED WORKERS
Romero-Mesones C, Cruz MJ, Alobid I et al. J Allergy Clin Immunol Pract. 2023 Jun 28:S2213-2198(23)00706-7. doi: 10.1016/j.jaip.2023.06.040. Epub ahead of print. HIGHLIGHTS What is already known about this topic?Exposure to certain agents in the workplace can trigger occupational asthma or work-exacerbated asthma, both of which come under the heading of work-related asthma. Up to […]
High apoptotic endothelial microparticle levels measured in asthma with elevated IgE and eosinophils
Open Access Yael Strulovici-Barel, Robert J. Kaner & Ronald G. Crystal Respiratory Research volume 24, Article number: 180 (2023) Abstract While asthma is considered an inflammatory-mediated airway epithelial and smooth muscle disorder, there is increasing evidence of airway capillary endothelial dysfunction associated with vascular remodelling and angiogenesis in some individuals with this condition. The inflammation is typically characterized as type-2 high (eosinophilic) vs […]
Systemic Corticosteroids for Treating Respiratory Diseases: Less Is Better, but… When and How Is It Possible in Real Life?
Review – Open Access Andrea S. Melani, Sara Croce, Lucia Cassai, Giusy Montuori, Gaia Fabbri, Maddalena Messina, Magda Viani & Elena Bargagli Pulm Ther (2023). https://doi.org/10.1007/s41030-023-00227-x Abstract Systemic corticosteroids (CSs), a keystone in pulmonology, are drugs with strong antiinflammatory activity. They are cheap, easily available, and accessible, but with common and serious side effects. Moreover, the use of exogenous CSs may suppress the […]
Safety and Effectiveness of As-Needed Formoterol in Asthma Patients Taking Inhaled Corticosteroid (ICS)-Formoterol or ICS-Salmeterol Maintenance Therapy
Reddel HK, Brusselle G, Lamarca R, Gustafson P, Anderson GP, Jorup C. J Allergy Clin Immunol Pract. 2023 Apr 11:S2213-2198(23)00398-7. doi: 10.1016/j.jaip.2023.03.046. Epub ahead of print. Background As-needed low-dose inhaled corticosteroid (ICS)-formoterol reliever is recommended in patients with asthma prescribed maintenance ICS-formoterol. Clinicians often ask whether ICS-formoterol reliever can be used with other maintenance ICS-long-acting […]
An update on asthma diagnosis
Charis Armeftis , MD, Christina Gratziou , MD, PhD, Nikolaos Siafakas , MD, PhD, Paraskevi Katsaounou , MD, PhD, Zoi Dorothea Pana , MD, MSc, PhD & Petros Bakakos , MD, PhD Journal of Asthma, DOI: 10.1080/02770903.2023.2228911 Abstract Objective Asthma imposes a significant health and socioeconomic burden with an average prevalence impacting 5-10% of the global population. The aim of this narrative review is […]
Objective Assessment of Adherence and Inhaler Technique among Asthma and COPD Patients in London: A Study in Community Pharmacies Using an Electronic Monitoring Device.
Hesso I, Nabhani-Gebara S, Kayyali R. Pharmacy. 2023; 11(3):94. BACKGROUND: The INhaler Compliance Assessment (INCATM ) device is an electronic monitoring device (EMD) that assesses both patient’s adherence and inhaler technique (IT). This study aimed, first, to assess the value of using the INCATM device as an objective measure during medicine use review (MUR) consultations provided […]
New for Journal of Asthma online now:
Research Article The association of varying treatment thresholds of mepolizumab on asthma exacerbations in adultsJaclyn Davis MD, Pamela M. McMahon PhD, Andrew Simon MPH, Katherine Haffenreffer BS, Aziza Jamal-Allial PhD, Cheryl N. McMahill-Walraven PhD, Anne Marie Kline MS, Jeffrey S. Brown PhD, Melissa K. Van Dyke PhD, Rupert W. Jakes PhD & Ann Chen Wu […]
Dexpramipexole Proves Effective as Oral Therapy for Eosinophilic Asthma
Colby Stong The oral asthma therapy dexpramipexole significantly reduced blood eosinophil counts and was well tolerated in patients with inadequately controlled moderate to severe eosinophilic asthma, investigators reported in the Journal of Allergy and Clinical Immunology. Dexpramipexole, an oral therapy initially developed to treat amyotrophic lateral sclerosis (ALS), was unexpectedly found to decrease blood eosinophil counts […]