Intranasal steroid use and COVID-19 mortality among patients with asthma and COPD: A retrospective cohort study.
Hernandez Santiago V, Fagbamigbe AF, Sullivan FM, Agrawal U, Morales D, McCowan C, Lipworth B. Ann Allergy Asthma Immunol. 2023 Jul 5:S1081-1206(23)00487-8. doi: 10.1016/j.anai.2023.06.026. Abstract Background Systemic corticosteroids have been widely used for treating patients with severe acute respiratory distress syndrome. Inhaled corticosteroids may have a protective effect for treating acute coronavirus disease 2019 (COVID-19); […]
Basic clinical management of preschool wheeze
REVIEW ARTICLE – Open Access Andrew Bush Pediatr Allergy Immunol. 2023 Jul;34(7):e13988. doi: 10.1111/pai.13988. Abstract Preschool wheeze is very common and often difficult to treat. Most children do not require any investigations; only a detailed history and physical examination to ensure an alternative diagnosis is not being missed; and the differential diagnosis, and hence investigation […]
New for Journal of Asthma online now
Case Report Long-term use of mepolizumab in a case of chronic eosinophilic pneumonia: extending interval dosingAlicia Prieto-García MD, PhD, María Isabel Peligros MD, Isabel Pérez Tamayo MD, José Manuel Zubeldia MD, PhD, Luis Álvarez-Sala MD, PhD & Cristina Lavilla MDPages: 1-3 | DOI: 10.1080/02770903.2023.2239343 Research Article Doxycycline may be more clinically effective in type 2 chronic […]
Obesity associated with worse oscillometry-defined small airway dysfunction in asthma
Key takeaways: Differences in small airway dysfunction persisted despite similarities in spirometry. Patients in one of the four patient clusters generally were older and female with obesity and more frequent exacerbations. Patients with both asthma and obesity had significantly worse small airway dysfunction as defined by oscillometry compared with patients who did not have obesity, […]
Chronic intermittent hypoxia increases airway hyperresponsiveness during house dust mites exposures in rats
Correspondence – Open Access Mihaela Teodorescu, Ruolin Song, Jacqueline A. Brinkman & Ronald L. Sorkness Respiratory Research volume 24, Article number: 189 (2023) Abstract Introduction Accumulating clinical evidence links Obstructive Sleep Apnea (OSA) with worse outcomes of asthma, but impact on airway function remains sparsely studied. We tested effects of Chronic Intermittent Hypoxia (CIH) – a hallmark of OSA – on airway hyperresponsiveness (AHR), […]
New for Journal of Asthma online now:
CASE REPORT Another case of preventable death from asthmaCinthia Vila Nova Santana PhD, Gabriela Pimentel Pinheiro MSc, Givaneide S. Lima MSc, Jamille Souza Fernandes PhD & Álvaro A. Cruz MDPages: 1-4 | DOI: 10.1080/02770903.2023.2234981 Omalizumab rescue therapy in refractory status asthmaticusSanjana Chetana Shanmukhappa MD, Arun Kumar PharmD, Akash Dey PharmD, Janani J.V.S. PharmD, Srivatsa Lokeshwaran […]
Criteria to evaluate efficacy of biologics in asthma: a Global Asthma Association survey
Angelica Tiotiu, Andras Bikov, Francisco-Javier Gonzalez-Barcala, Silviya Novakova, Plamena Novakova, Herberto Chong-Neto, Pierachille Santus, Ignacio Ansotegui, Juan Carlos Ivancevich, Krzysztof Kowal, Stefan Mihaicuta, Denislava Nedeva, Gorgio Walter Canonica, Jonathan A. Bernstein, Louis Philippe Boulet & Fulvio Braido (2023) Expert Review of Respiratory Medicine, 17:6, 507-516 ABSTRACT Background Currently, there are no universally accepted criteria to measure the response to […]
Association of selected inflammatory biomarkers with cough reflex sensitivity in asthmatic children
P Kunč , J Fábry, M Grendár, P Ferenc, T Strachan, K Ištvánková, T Hurtová, R Péčová Physiol Res. 2023 Jul 14;72(3):349-358. Abstract Bronchial asthma is the most common chronic respiratory disease of childhood. Cough is one of its defining symptoms. This study investigated the associations between selected inflammatory biomarkers and cough reflex sensitivity after capsaicin inhalation in children with mild and moderate […]
Journal of Asthma, Volume 60, Issue 9, September 2023 is now available online
This new issue contains the following articles: Review Open-inhaler versus single-inhaler triple therapy (long-acting muscarinic antagonist, inhaled corticosteroid, and long-acting β2-agonist) in asthma patients: a narrative review | Michael E. Wechsler MD & John J. Oppenheimer MDPages: 1633-1645 | DOI: 10.1080/02770903.2023.2188556 Research Articles Prevalence and risk factors for self-reported asthma among sámi in Sweden: a cross-sectional study | Emil Xabier […]
LPS binding protein and activation signatures are upregulated during asthma exacerbations in children
Research – Open Access Anya C. Jones, Jonatan Leffler, Ingrid A. Laing, Joelene Bizzintino, Siew-Kim Khoo, Peter N. LeSouef, Peter D. Sly, Patrick G. Holt, Deborah H. Strickland & Anthony Bosco Respir Res 24, 184 (2023). https://doi.org/10.1186/s12931-023-02478-3 Abstract Asthma exacerbations in children are associated with respiratory viral infection and atopy, resulting in systemic immune activation and infiltration of immune cells into the airways. The gene networks […]