Role of Immunotherapy in the Treatment of Asthma

SYSTEMATIC REVIEW Download PDF 2.9 MB Related Files Download Evidence Summary [PDF · 473.4 KB] These reports are available in PDF only (Full Report [3.0 MB]; Evidence Summary [370 KB]). People using assistive technology may not be able to fully access information in these files. For additional assistance, please contact us. Key Messages Purpose of Review To assess the efficacy and safety […]

Severe, eosinophilic asthma in primary care in Canada: a longitudinal study of the clinical burden and economic impact based on linked electronic medical record data

Allergy, Asthma & Clinical Immunology Research – Open Access Don Husereau, Jason Goodfield, Richard Leigh, Richard Borrelli, Michel Cloutier and Alain Gendron Allergy, Asthma & Clinical Immunology 2018 14:15 https://doi.org/10.1186/s13223-018-0241-1 Abstract Background Stratification of patients with severe asthma by blood eosinophil counts predicts responders to anti-interleukin (IL)-5 (mepolizumab and reslizumab) and anti-IL-5 receptor α (benralizumab) therapies. This study characterized patients with severe asthma who could qualify for these […]

New Article From Asthma Research and Practice: Clinical characteristics and comorbidities of elderly asthmatics who attend allergy clinics

Asthma Research and Practice Research – Open Access   Anahí Yáñez, Marcela Soria, Susana De Barayazarra, Nancy Recuero, Francisco Rovira, Edgardo Jares, Ana María Stok, Sergio Nemirovsky andCarlos Bueno Asthma Research and Practice 2018 4:5 Abstract Background To date, few studies have focused on the clinical and allergic characteristics of asthma in the elderly, defined as asthma in people aged 60 or over. Thus, we propose to identify and study the clinical and allergic characteristics […]

The course of asthma during pregnancy in a recent, multicase–control study on respiratory health

Allergy, Asthma & Clinical Immunology Short Report – Open Access A. Grosso, F. Locatelli, E. Gini, F. Albicini, C. Tirelli, I. Cerveri and A. G. Corsico Allergy, Asthma & Clinical Immunology 2018 14:16 https://doi.org/10.1186/s13223-018-0242-0 Abstract Background Over the years it has been widely stated that approximately one-third of asthmatic women experience worsening of the disease during pregnancy. However, the literature has not been reviewed systematically and the meta-analytic reviews include old […]

Nerve ablation after bronchial thermoplasty and sustained improvement in severe asthma

Research article – Open Access – Open Peer Review BMC Pulmonary Medicine BMC series – open, inclusive and trusted 2018 18:29   N. Facciolongo, A. DiStefano, V. Pietrini, C. Galeone, F. Bellanova, F. Menzella, N. Scichilone, R. Piro, G. L. Bajocchi, B. Balbi, L. Agostini, P. P. Salsi, D. Formisano and M. Lusuardi https://doi.org/10.1186/s12890-017-0554-8 Open Peer Review reports Abstract Background Bronchial thermoplasty (BT) is a non-pharmacological intervention for severe asthma whose mechanism of action is not completely explained by a reduction of airway smooth muscle […]

Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma

BMC Pulmonary Medicine Research article – Open Access – Open Peer Review   Mark D. DeBoer, Brenda R. Phillips, David T. Mauger, Joe Zein, Serpil C. Erzurum, Anne M. Fitzpatrick, Benjamin M. Gaston, Ross Myers, Kristie R. Ross, James Chmiel, Min Jie Lee, John V. Fahy, Michael Peters, Ngoc P. Ly, Sally E. Wenzel, Merritt L. Fajt, Fernando Holguin, Wendy C. Moore, Stephen P. Peters, Deborah Meyers, Eugene R. Bleecker, Mario Castro, Andrea M. Coverstone, Leonard B. Bacharier, Nizar N. Jarjour, Ronald L. Sorkness, Sima Ramratnam, Anne-Marie Irani, Elliot Israel, Bruce Levy, Wanda Phipatanakul, Jonathan M. Gaffin and W. Gerald Teague Email author   BMC Pulmonary Medicine BMC series – open, […]

WCA 2018 – Abstract Submission

Submission Deadline June 08, 2018 Abstract Guidelines Specifications: Rationale: A brief statement of purpose of the study and the hypothesis to be tested. Methods: Summarize the predictors and outcomes analyzed, as well as the methods used. For abstracts reporting clinical research, a sentence or phrase presenting the most important selection criteria for subjects should be included. Results: Provide […]

World Congress of Asthma 2018 – Scientific Program Committee’s Message

Significant achievements have been accomplished in the last few years to better understanding what asthma is, how it should be assessed in regards to control and severity and what its optimal therapy is. Unfortunately, these improvements in our understanding of the disease have not always translated into better asthma management. The 2018 World Congress on […]

A case of allergic bronchopulmonary aspergillosis successfully treated with mepolizumab

BMC Pulmonary Medicine BMC series – open, inclusive and trusted 2018 18:53 Takeshi Terashima,T aro Shinozaki, Eri Iwami,Takahiro Nakajima and Tatsu Matsuzaki https://doi.org/10.1186/s12890-018-0617-5 Open Peer Review reports Abstract Background Allergic bronchopulmonary aspergillosis (ABPA) is an allergic pulmonary disease comprising a complex hypersensitivity reaction to Aspergillus fumigatus. Clinical features of ABPA are wheezing, mucoid impaction, and pulmonary infiltrates. Oral corticosteroids and anti-fungal agents are standard […]

Pulmonary interstitial emphysema in fatal asthma: case report and histopathological review

Case report – Open Access – Open Peer Review Thais Mauad, Felipe B. P. do Nascimento, Marisa Dolhnikoff, Milena C. M. Picka, Paulo H. N. Saldiva and on behalf of BIAS BMC Pulmonary Medicine BMC series – open, inclusive and trusted  18:50, 2018 Open Peer Review reports Abstract Background Mortality related to asthma has decreased worldwide since the introduction of inhaled corticosteroid therapy in the past decades. However, there are still some asthma […]