The WEB-based Asthma Control: an intriguing connection or a dangerous hazard?
REVIEW Carlo Lombardi, Giovanni Passalacqua and Giorgio Walter Canonica Asthma Research and Practice 201 51:15 DOI: 10.1186/s40733-015-0017-z Abstract Globally, an estimated 300 million people have asthma, presenting a considerable and increasing burden of disease for healthcare systems, families, and patients themselves. Despite two decades of guidelines, asthma seems to remain not optimally controlled in a substantial proportion of people. The achievement of asthma […]
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Isocyanate exposure and asthma in the UK vehicle repair industry
Occup Med (Lond) (2015) 65 (9):713-718. S. J. Stocks1, K. Jones2, M. Piney3 and R. M. Agius41 NIHR Greater Manchester Primary Care Patient Safety Translational Research Centre, Centre for Primary Care, Institute of Population Health, University of Manchester, Manchester M13 9PL, UK, 2 Health & Safety Laboratory, Buxton, Derbyshire SK17 9JN, UK,3 Health & Safety Executive, Bootle, Merseyside L20 7HS, UK, 4 Centre for Occupational and Environmental Health, Centre for Epidemiology, […]
Three-month validation of a turbuhaler electronic monitoring device: implications for asthma clinical trial use
BMJ Open Resp Res 2015;2:e000097 doi:10.1136/bmjresp-2015-000097 Janine Pilcher1,2, Philippa Shirtcliffe1,2, Mitesh Patel2,3, Steve McKinstry2, Terrianne Cripps1,2, Mark Weatherall1,4 and Richard Beasley1,2 Abstract Background Electronic monitoring of inhaled asthma therapy is suggested as the ‘gold standard’ for measuring patterns of medication use in clinical trials. The SmartTurbo (Adherium (NZ) Ltd, Auckland, New Zealand) is an electronic monitor for use with a turbuhaler device (AstraZeneca, UK). […]
Sickle cell disease: wheeze or asthma?
REVIEW Robyn T. Cohen, Elizabeth S. Klings and Robert C. Strunk Asthma Research and Practice20151:14 DOI: 10.1186/s40733-015-0014-2 Abstract Sickle cell disease (SCD) is the most common life-limiting genetic disease among African Americans, affecting more than 100,000 people in the United States. Respiratory disorders in patients with sickle cell disease have been associated with increased morbidity and mortality. Associations between asthma and pain, acute chest […]
Asthma changes at a Pediatric Intensive Care Unit after 10 years: Observational study
Al-Eyadhy AA, Temsah MH, Alhaboob AA, Aldubayan AK, Almousa NA, Alsharidah AM, Alangari MI, Alshaya AM. Ann Thorac Med 2015;10:243-8 Abstract Objectives: To describe the change in the management, and outcome of children with acute severe asthma (ASA) admitted to Pediatric Intensive Care Unit (PICU) at tertiary institute, as compared to previously published report in 2003.Methods : […]
Anti-IgE treatment, airway inflammation and remodelling in severe allergic asthma: current knowledge and future perspectives
Konstantinos Samitas, Vasiliki Delimpoura, Eleftherios Zervas, Mina Gaga DOI: 10.1183/16000617.00001715 Published 1 December 2015 Article Figures & Data Info & Metrics PDF Abstract Asthma is a disorder of the airways involving various inflammatory cells and mediators and characterised by bronchial hyperresponsiveness, chronic inflammation and structural alterations in the airways, also known as remodelling. IgE is an important mediator of allergic reactions and has a […]
Bronchial thermoplasty: a review of the evidence
DOI: http://dx.doi.org/10.1016/j.anai.2015.11.002 Chelle Pope Wilhelm, MD , Bradley E. Chipps, MD Abstract Objective: To provide a review of the literature regarding bronchial thermoplasty in the treatment of asthma. Data Sources: PubMed was searched without time limitations using the key term bronchial thermoplasty alone and in combination with the key terms asthma and treatment of asthma. Other key terms included cost-effectiveness and bronchial thermoplasty, cost-effectiveness and omalizumab, and epidemiology andasthma. Study Selection: Qualifying articles included […]
Uncovering Asthma Report
The impact of severe asthma has far reaching effects on society as a whole and often leaves people unable to fully contribute economically. The Uncovering Asthma survey found that a significant proportion of people with severe asthma (30%) have taken time off work, university or their studies in the past 12 months due to hospitalisation […]
Small airway dysfunction and bronchial asthma control : the state of the art
The official journal of Interasma REVIEW Marcello Cottini, Carlo Lombardi,Claudio Micheletto Asthma Research and Practice 20151:13 DOI: 10.1186/s40733-015-0013-3 Abstract According to national and international guidelines, achieving and maintaining asthma control is a major goal of disease management. In closely controlled clinical trials, good asthma control can be achieved , with the medical treatments currently available, in the majority of patients , […]